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DDX54 polyclonal antibody

货号: BS61585

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS61585

Product Name :DDX54 polyclonal antibody

Swiss-Prot :Q8TDD1

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX54 (DEAD polypeptide 54), also known as DP97, is an 881 amino acid protein that contains 2 bipartite nuclear localization signals, 3 nuclear receptor boxes (LXXLL motifs), a potential CoRNR box, and several stretches of glutamate and lysine residues. DDX54 is ubiquitously expressed, with highest expression in pancreas and lung. DDX54 co-localizes with ERα to structures in the nucleoplasm. DDX54 represses ERα transcriptional activity and acts as a nuclear receptor co-repressor against ERβ, progesterone, glucocorticoid and RARα

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DDX54 polyclonal antibody detects endogenous levels of DDX54 protein.

BiowMW :~ 98 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATP-dependent RNA helicase DDX54 ; ATP-dependent RNA helicase DP97; DEAD box RNA helicase 97 kDa; DEAD box protein 54

Immunogen :Synthetic peptide, corresponding to amino acids 602-646 of Human DDX54

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DDX54 polyclonal antibody at 1:500 dilution Lane1:HCC827 whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug)