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ALPK1 polyclonal antibody

货号: BS61558

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS61558

Product Name :ALPK1 polyclonal antibody

Swiss-Prot :Q96QP1

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. α-protein kinase 1, also known as ALPK1, LAK or KIAA1527, is a 1,244 amino acid protein that contains one α-type protein kinase domain and belongs to the protein kinase superfamily. Expressed at high levels in liver, α-protein kinase 1 recognizes and phosphorylates specific phosphorylation sites that are surrounded by peptides which have an å-helical conformation. One of the targets of å-protein kinase 1 is Myosin I and, via its ability to phosphorylate Myosin I, α-protein kinase 1 is thought to play an important role in the apical trafficking of vesicles carrying raft-associated sucrase-isomaltase (SI).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ALPK1 polyclonal antibody detects endogenous levels of ALPK1 protein.

BiowMW :~ 139 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Alpha-protein kinase 1; Chromosome 4 kinase; Lymphocyte alpha-protein kinase

Immunogen :Synthetic peptide, corresponding to amino acids 11-55 of Human ALPK1

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ALPK1 polyclonal antibody at 1:500 dilution Lane1:L02 whole cell lysate(40ug) Lane2:HCT116 whole cell lysate(40ug) Lane3:HCC827 whole cell lysate(40ug)