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DUS2L polyclonal antibody

货号: BS61523

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61523

Product Name :DUS2L polyclonal antibody

Swiss-Prot :Q9NX74

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :DUS2L (tRNA-dihydrouridine synthase 2-like), also known as URLC8 (upregulated in lung cancer protein 8) or SMM1, is a 493 amino acid member of the DUS protein family. Localized to cytoplasm and endoplasmic reticulum, DUS2L uses FAD as a cofactor to catalyze the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. DUS2L contains one DRBM (double-stranded RNA-binding) domain and has been found to interact with ProRS. DUS2L is upregulated in most lung cancer cells and has weak expression in normal heart, skeletal muscle and placenta. The gene that encodes DUS2L maps to human chromosome 16q22.1 and murine chromosome 8 D3.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DUS2L polyclonal antibody detects endogenous levels of DUS2L protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase 2; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2

Immunogen :Synthetic peptide, corresponding to amino acids 441-485 of Human DUS2L.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DUS2L polyclonal antibody at 1:500 dillution Lane1:HCT-116 whole cell lysate(40μg) Lane2:The Lung tissue lysate of Mouse(40μg) Lane3:The Lung tissue lysate of Rat(40μg)