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IL4 polyclonal antibody

货号: BS61515

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61515

Product Name :IL4 polyclonal antibody

Swiss-Prot :P05112

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNFβ and IFN-γ, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2, and IgG3.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-4 polyclonal antibody detects endogenous levels of IL-4 protein.

BiowMW :~ 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin-4; Interleukin 4; Interleukin4; B-cell stimulatory factor 1; BSF-1; BSF1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra; IL4

Immunogen :Synthetic peptide, corresponding to amino acids 93-137 of Human IL4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IL-4 polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate(40ug) Lane2:The testis tissue lysate of Mouse(40ug) Lane3:The testis tissue lysate of Rat(40ug) Lane4:The thymus tissue lysate of Rat(40ug) Lane5:THP-1 whole cell lysate(40ug)