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ADRA1D polyclonal antibody

货号: BS61380

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS61380

Product Name :ADRA1D polyclonal antibody

Swiss-Prot :P25100

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :α1D-adrenergicreceptors(α1D-ARs)couple to Gq/11 and participate directly in sympatheticregulation ofsystemic blood pressure byvasoconstriction. α1D-AR can form hetero-oligomers with α1B receptors. α1D-AR transcripts are abundant in prostate and aorta. α1A adrenergicreceptors(α1A-ARs) mediate actionsin the sympathetic nervoussystem through the binding of the catecholamines, epinephrine and norepinephrine. α1A-adrenergic receptors couple to Gq/11 and regulate blood pressure due to changesin vascular tone and cardiac output. Alternative splicing of this gene generatesfour isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. α1A-AR transcripts are abundant in heart, brain, liver, and prostate. α1A-AR transcriptsizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. α1A-AR transcriptsizes of 6.0, 4.0 and 3.0 kb transcripts have been detected in heart, and 6.0 kb and 4.0 kb transcripts have been detected in prostate.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ADRA1D polyclonal antibody detects endogenous levels of ADRA1D protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Alpha-1D adrenergic receptor; Alpha-1A adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor; Alpha-adrenergic receptor 1a; ADRA1D; ADRA1A

Immunogen :Synthetic peptide, corresponding to amino acids456-501 of Human ADRA1D

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of ADRA1D polyclonal antibody at 1:500 dillution Lane1:MCF-7 whole cell lysate(40μg)