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GYS1 polyclonal antibody

货号: BS61282

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61282

Product Name :GYS1 polyclonal antibody

Swiss-Prot :P13807

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB 1:500 - 1:1000 IHC 1:50 - 1:100

Background :Glycogen [starch] synthase belongs to the mammalian/fungal glycogen synthase family of proteins. Two forms of this protein exist, a liver form and a muscle form, both of which have the same function in the glycogen biosynthesis pathway. Glycogen synthase transfers the glycosyl residue from UDP-Glucose to the nonreducing end of å-1,4-glucan. The liver glycogen synthase protein is truncated by 34 amino acids compared to the muscle form. However, these enzymes differ significantly in their amino- and carboxyl-terminal regions. Muscle glycogen synthase serves to fuel muscular activity only and is regulated by muscle contraction and by catecholamines. Liver glycogen synthase mediates blood glucose homeostasis in response to nutritional cues. Defects in the gene encoding liver glycogen synthase results in glycogen storage disease type 0 (GSD0), a rare form of fasting ketotic hypoglycemia.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GYS1 polyclonal antibody detects endogenous levels of GYS1 protein.

BiowMW :~ 95 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Actin Dynamics,Insulin &Glucose Signaling,

Alternative Name :Glycogen [starch] synthase, muscle (EC:2.4.1.11); GYS1; GYS

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GYS1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of GYS1 expression in HEK293T (A), LO2 (B), HepG2 (C), AML12 (D), H9C2 (E) whole cell lysates.

Immunohistochemical analysis of GYS1 staining in human lymph formalin fixed paraffin embedded tissue section.

免疫沉淀（IP）