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GNG5 polyclonal antibody

货号: BS61200
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS61200
Product Name :GNG5 polyclonal antibody
Swiss-Prot :P63218
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB
Application_all :WB: 1:500~1:1000
Background :Heterotrimeric G proteinsfunction to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus(a photon, pheromone, odorant, hormone or neuro transmitter) while the effectors(e.g., adenylcyclase),which act to generate one ormore intracellula rmessengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits,since these proteins bind and hydrolyze GTP andmost obvously regulate the activity of the beststudied effectors. Evidence, however, has established an important regulatory role for the βγ subunits. It is becoming increasingly clear that different G protein complexes expressed in diffeent tissues carry structurally distinct members of the γ aswell astheαand β subunits and that preferential associations between members of subunit families increase G protein functional diversity.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :GNG5 polyclonal antibody detects endogenous levels of GNG5 protein.
BiowMW :~ 7 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5; GNG5; GNGT5
Immunogen :A synthetic peptide corresponding to residues in Human GNG5.
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of GNG5 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:RAW264.7 whole cell lysate Lane3:H9C2 whole cell lysate
  • GNG5 is a novel regulator of Aβ42 production in Alzheimer’s disease
    Journal10.1038/s41419-024-07218-z
    ApplicationDot Blot
    IF8.1
    SpeciesHuman

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com