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GTPBP5 polyclonal antibody

货号: BS61198

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61198

Product Name :GTPBP5 polyclonal antibody

Swiss-Prot :Q9H4K7

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP5 (GTP-binding protein 5), also known as OBGH1, is a 406 amino acid small G protein that contains an amino-terminal mitochondria-localization signal. Knockdown of GTPBP5 mRNA results in abnormal nuclear morphologies and elongated mitochondria. In vitro studies demonstrate that GTPBP5 exhibits GTPase activity, cycling between an active GTP-bound state and an inactive GDP-bound state. Activation of GTPases usually results in rearrangements of filamentous actin and the formation of actin stress fibers.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GTPBP5 polyclonal antibody detects endogenous levels of GTPBP5 protein.

BiowMW :~ 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Mitochondrial ribosome-associated GTPase 2; GTP-binding protein 5; Protein obg homolog 1; ObgH1; MTG2; GTPBP5; OBGH1

Immunogen :A synthetic peptide corresponding to residues in Human GTPBP5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of GTPBP5 polyclonal antibody at 1:500 dilution Line1:A549 whole cell lysate Line2:Hela whole cell lysate Line3:PC12 whole cell lysate Line4:sp20 whole cell lysate