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ADAMDEC1 polyclonal antibody

货号: BS61122

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS61122

Product Name :ADAMDEC1 polyclonal antibody

Swiss-Prot :O15204

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :ADAMDEC1 (ADAM-like, decysin 1), also known as decysin, is a 470 amino acid secreted protein that belongs to the disintegrin metalloproteinase family. Expressed primarily in dendritic cells (DCs) of the small intestine, spleen and lymph nodes, ADAMDEC1 can bind one zinc ion per subunit and is thought to be involved in controlling the immune response. ADAMDEC1 expression is induced in maturing DC cells in response to T-cell signals and its expression is upegulated during differentiation of primary monocytes into macrophages. ADAMDEC1 contains one peptidase M12B domain, a prematurely terminated disintegrin domain and, unlike other ADAM family members, does not have an intracellular tail or a cysteine-rich domain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ADAMDEC1 polyclonal antibody detects endogenous levels of ADAMDEC1 protein.

BiowMW :~ 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ADAM DEC1 (EC:3.4.24.-); A disintegrin and metalloproteinase domain-like protein decysin-1; ADAM-like protein decysin-1; ADAMDEC1

Immunogen :A synthetic peptide corresponding to residues in Human ADAMDEC1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ADAMDEC1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:RAW264.7 whole cell lysate Lane3:H9C2 whole cell lysate

Immunohistochemistry (IHC) analyzes of ADAMDEC1 pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50,showing cytoplasm and secreted staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.