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ABHD14B polyclonal antibody

货号: BS61119

价格：￥ 660

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61119

Product Name :ABHD14B polyclonal antibody

Swiss-Prot :Q96IU4

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eightstranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer’s disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members. Most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD14B is a 210 amino acid protein that localizes to both the cytoplasm and the nucleus where it exists as 2 alternatively spliced isoforms.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ABHD14B polyclonal antibody detects endogenous levels of ABHD14B protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein ABHD14B; Alpha/beta hydrolase domain-containing protein 14B; Abhydrolase domain-containing protein 14B; CCG1-interacting factor B; ABHD14B; CIB

Immunogen :Synthetic peptide, corresponding to Human ABHD14B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ABHD14B polyclonal antibody at 1:500 dilution Lane1:The Spleen tissue lysate of Mouse(20ug) Lane2:The Thymus tissue lysate of Rat(20ug) Lane3:Jurkat whole cell lysate(40ug) Lane4:K562 whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(40ug)