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ETV4 polyclonal antibody

货号: BS61024

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS61024

Product Name :ETV4 polyclonal antibody

Swiss-Prot :P43268

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Several members of the Ets gene family are known to encode sequence-specific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-a. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ETV4 polyclonal antibody detects endogenous levels of ETV4 protein.

BiowMW :~ 59 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ETS translocation variant 4; Adenovirus E1A enhancer-binding protein; E1A-F; Polyomavirus enhancer activator 3 homolog; Protein PEA3; ETV4; E1AF; PEA3

Immunogen :A synthetic peptide corresponding to residues in Human ETV4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ETV4 pAb at 1:500 dilution Lane1:H9C2 whole cell lysate(40ug) Lane2:CT-26 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug)