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IGLL1 (C194) polyclonal antibody （KU）

货号: BS60959

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60959

Product Name :IGLL1 (C194) polyclonal antibody （KU）

Swiss-Prot :P15814

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:203

Background :Lambda 5 (also called Immunoglobulin lambda-like polypeptide 1 or CD179b antigen) and VpreB comprise the surrogate light chain of the pre-B cell receptor complex. SL chain is also part of a quality control mechanism that tests a m-chain for its ability to pair with conventional L chains. It can form Ig-like complexes with the heavy (H) chain, the DHJHC m-protein or the p55 chain. Production of the surrogate light chain begins at the stage of pro-B cells, continues during the pre-B-cell stage and halts at the immature B cell stage. Once pre-BCR is expressed, SL chain expression is turned off. As pre-B II cells proliferate, SL is diluted out, thus limiting pre-BCR formation. Lambda 5 is critical for B cell development in mammals. Expression of Lambda 5 is highest in liver, pre- B-lymphocytes and bone marrow, the major source of B cell precursors.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IGLL1 (C194) polyclonal antibody detects endogenous levels of IGLL1 protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Immunoglobulin lambda-like polypeptide 1; CD179 antigen-like family member B; Ig lambda-5; Immunoglobulin omega polypeptide; Immunoglobulin-related protein 14.1; CD179b; IGLL1; IGL1

Immunogen :A synthetic peptide corresponding to residues in Human IGLL1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IGLL1 (C194) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:Myla2059 whole cell lysate(40ug) Lane3:K562 whole cell lysate(40ug)