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IL2RA polyclonal antibody

货号: BS60896

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS60896

Product Name :IL2RA polyclonal antibody

Swiss-Prot :P01589

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The IL-2 receptor is amulticomponentcomplexconsisting of three subunits,α, β and γ, each ofwhich isrequired for high-affinity binding of IL-2. Theαchain functions primarilyin binding IL-2, whereasthe β and γ chainscontribute to IL-2 binding and are essential to IL-2-induced activation ofsignaling pathways leading to T cell growth. Both IL-4R and IL-7R were initially described as single chain, high-affinityligand-binding cytokine receptors. However, it is now well established that the IL-2Rγ chain functions as a second subunit of the high affinityIL-4R and IL-7R receptors. Consequently, the originally described subunits of these latter receptors are nowreferred to asIL-4Rαand IL-7Rα, respectively,while the common subunit isreferred to as γc. Although the common γ chain enhancesligand binding in these three cytokine receptors, it has no capacityto bind these ligands on its own. There is evidence that the γcchain is also a subunit of IL-13R.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL2RA polyclonal antibody detects endogenous levels of IL2RA protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25; IL2RA

Immunogen :A synthetic peptide corresponding to residues in Human IL2RA.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IL2RA polyclonal antibody at 1:500 dilution Lane1:Thp-1 whole cell lysate Lane2:H9C2 whole cell lysate Lane3:Raw264.7 whole cell lysate