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ANKRD20A3 polyclonal antibody

货号: BS60731

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS60731

Product Name :ANKRD20A3 polyclonal antibody

Swiss-Prot :Q5VUR7

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ANKRD20A3 polyclonal antibody detects endogenous levels of ANKRD20A3 protein.

BiowMW :~ 94 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ankyrin repeat domain-containing protein 20A3; ANKRD20A3

Immunogen :A synthetic peptide corresponding to residues in Human ANKRD20A3

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ANKRD20A3 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate

Immunohistochemistry (IHC) analyzes of ANKRD20A3 pAb in paraffin-embedded human stomach carcinoma tissue at 1:50,showing membrane and cytoplasmic staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.