产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

HSP60 polyclonal antibody

货号: BS6072

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6072

Product Name :HSP60 polyclonal antibody

Swiss-Prot :P10809

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC,IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background :HSPs (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins, and the HSP 110 family. The constitutively expressed mitochondrial protein HSP 60 shares the ability to recognize and stabilize proteins during folding, assembly and disassembly with other HSP family members. The mitochondrial and cytosolic localization of HSP 60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker forr γ/δ T cell recognition.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HSP60 polyclonal antibody detects endogenous levels of HSP60 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Mitochondrial Control of Apoptosis,

Alternative Name :60 kDa heat shock protein, mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein; HSPD1; HSP60

Immunogen :Recombinant full length Human HSP60.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of HSP60 polyclonal antibody in extracts from T470, Hela, NIH3T3, PC12, COS1 cells and mouse heart, brain, kidney tissues.

Immunohistochemistry (IHC) analysis of HSP60 polyclonal antibody in paraffin-embedded Human Stomach Cancer tissue.

Immunofluorescence analysis of Hela cells, using HSP60 polyclonal antibody

1-oxoeudesm-11(13)-ene-12,8α-lactone-induced apoptosis via ROS generation and mitochondria activation in MCF-7 cells

JournalArchives Of Pharmacal Research

ApplicationWB

IF2.934

SpeciesHuman

PMID21910054
miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation

JournalCell Death & Disease

ApplicationWB

IF5.959

SpeciesHuman

PMID28981116
Pink1/PARK2/mROS-Dependent Mitophagy Initiates the Sensitization of Cancer Cells to Radiation

JournalOxidative Medicine and Cellular Longevity

ApplicationWB

IF6.543

SpeciesHuman

PMID34306311