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HABP2 polyclonal antibody

货号: BS60689

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60689

Product Name :HABP2 polyclonal antibody

Swiss-Prot :Q14520

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The hyaluronan-binding protein 2 (HABP2), also designated plasma hyaluronan-binding protein (PHBP) or factor VII-activating protease, belongs to the peptidase S1 family and contains three EGF-like domains, one kringle domain and one peptidase S1 domain. HABP2 is a heterodimer that contains a heavy chain of 50 kDa and a light chain of 27 kDa, which are linked by a disulfide bond. HABP2 is ubiquitously expressed and acts as a serine protease with fibrinogen and fibronectin being the major substrates. HABP2 has been shown to cleave the alpha-chain at multiple sites and the beta-chain between lysine53 and lysine54, but not the gamma-chain of fibrinogen. Overexpression of HABP2 has been shown to occur in lung adenocarcinomas and may be a useful biomarker for that type of cancer.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HABP2 polyclonal antibody detects endogenous levels of HABP2 protein.

BiowMW :~ 63 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Hyaluronan-binding protein 2; Factor VII-activating protease; Factor seven-activating protease; FSAP; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding protein; HABP2; HGFAL; PHBP

Immunogen :A synthetic peptide corresponding to residues in Human HABP2

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of HABP2 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:PC12 whole cell lysate