产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

IL-1β polyclonal antibody

货号: BS6067

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6067

Product Name :IL-1β polyclonal antibody

Swiss-Prot :P01584

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB 1:500 - 1:1000 IHC 1:100 - 1:200

Background :Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-1β polyclonal antibody detects endogenous levels of IL-1β protein.

BiowMW :~ 31, 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,Inflammasonme Signaling,Necrotic Cell Death,

Alternative Name :Interleukin-1 beta; IL-1 beta; Catabolin; IL1B; IL1F2; IL-1β; IL1β

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-1 beta.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of IL-1 beta expression in Raw264.7 (A), mouse spleen (B), rat spleen (C), rat thymus (D), mouse thymus (E), Jurkat (F), THP1 (G) whole cell lysates.

Immunohistochemical analysis of IL-1 beta staining in human lung cancer formalin fixed paraffin embedded tissue section.

Penta-acetyl Geniposide Suppresses Migration, Invasion, and Inflammation of TNF-α-Stimulated Rheumatoid Arthritis Fibroblast-Like Synoviocytes Involving Wnt/β-Catenin Signaling Pathway

JournalInflammation

ApplicationWB

IF4.092

SpeciesHuman

PMID
Inhibition of ERK1/2 phosphorylation attenuates spinal cord injury induced astrocyte activation and inflammation through negatively regulating aquaporin-4 in rats

JournalBrain Research Bulletin

ApplicationWB, IF

IF4.077

SpeciesRat

PMID33592275
Blocking the LncRNA MALAT1/miR-224-5p/NLRP3 Axis Inhibits the Hippocampal Inflammatory Response in T2DM With OSA

JournalFrontiers in Cellular Neuroscience

ApplicationIF

IF3.921

SpeciesMouse

PMID32477065
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice

JournalFrontiers in Neuroscience

ApplicationWB

IF3.707

SpeciesMouse

PMID32581664
Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats

JournalOncology Reports

ApplicationWB

IF3.417

SpeciesRat

PMID33000240