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HLA-A/ B/ C polyclonal antibody

货号: BS60609

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS60609

Product Name :HLA-A/ B/ C polyclonal antibody

Swiss-Prot :P01891/P01892/P04439/P05534/ P10314/ P10316/ P13746/ P16189/ P18462/ P30443/ P30450/ P30453/ P30455/ P30456/ P30457/ P30512/ Q09160

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Major histocompatibility complex (MHC) molecules form an integral part of the immune response system. They are cell-surface receptors that bind peptides and present them to T lymphocytes. Human leukocyte antigens (HLAs) are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor. There are two classes of HLA antigens: class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-A, -B and -C encode membrane anchored heavy chains which heterodimerize with a light chain (b-2-Microglobulin) to form MHC-I. Polymorphisms yield hundreds of HLA-A, -B and -C alleles.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HLA-A/ B/ C polyclonal antibody detects endogenous levels of HLA-A/ B/ C protein.

BiowMW :~ 41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HLA class I histocompatibility antigen, A-68 alpha chain; Aw-68; HLA class I histocompatibility antigen, A-28 alpha chain; MHC class I antigen A*68; HLA-A; HLAA

Immunogen :A synthetic peptide corresponding to residues in Human HLA-A/ B/ C

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of HLA-A/ B/ C polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:H9C2 whole cell lysate