产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

HOXC8 polyclonal antibody

货号: BS60569

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60569

Product Name :HOXC8 polyclonal antibody

Swiss-Prot :P31273

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :HoxC8 (Homeobox protein Hox-C8, Hox-3A) is a 242 amino acid protein encoded by the human gene HOXC8. HoxC8 belongs to the Antp homeobox family and contains one homeobox DNA-binding domain. The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Homeobox region 3 contains at least seven homeoboxes within 160 kb of DNA. Overexpression of the HOXC8 transgene causes cartilage defects, the severity of which depends upon transgene dosage. This abnormal cartilage is characterized by an accumulation of proliferating chondrocytes and reduced maturation. Since HoxC8 is normally expressed in chondrocytes, it may be responsible for skeletal development other than pattern formation in a tissue-specific manner, hypothetically by controlling the progression of cells along the chondrocyte differentiation pathway.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HOXC8 polyclonal antibody detects endogenous levels of HOXC8 protein.

BiowMW :~ 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Homeobox protein Hox-C8; Homeobox protein Hox-3A; HOXC8; HOX3A

Immunogen :A synthetic peptide corresponding to residues in Human HOXC8

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of HOXC8 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate

Embryonic morphology observation and HOXC8 gene expression in crest cushions of Chinese Crested duck

JournalGene

ApplicationWB

IF3.688

SpeciesDuck

PMID30529099