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ANGPT4 polyclonal antibody

货号: BS60368

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS60368

Product Name :ANGPT4 polyclonal antibody

Swiss-Prot :Q9Y264

Host :Rabbit

Reactivity :Human

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. Ang-1 is an angiogenic factor that mediates blood vessel maturation and may be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), is a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression is restricted to sites of vascular remodeling. Ang-3 and Ang-4 represent the mouse and human counterparts of the same gene locus. The structural divergence of Ang-3 and Ang-4 cause their divergent functions. Ang-3 and Ang-4 have very different distributions in their respective species, and Ang-3 appears to act as an antagonist while Ang-4 appears to function as an agonist. Ang-3 and Ang-4 share all the main structural characteristics of Ang-1 and Ang-2 and are homologous throughout the signal peptide, N-terminal region, coiled-coil segment and Fibrinogen-like domain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ANGPT4 polyclonal antibody detects endogenous levels of ANGPT4 protein.

BiowMW :~ 56 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Angiopoietin-4; ANG-4; Angiopoietin-3; ANG-3; Angiopoietin4; ANG4; Angiopoietin3; ANG3; ANG3; ANG4

Immunogen :A synthetic peptide corresponding to residues in Human ANGPT4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ANGPT4 pAb at 1:500 dilution Lane1:HCC827 whole cell lysate(40ug) Lane2:H460 whole cell lysate(40ug) Lane3:H1792 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of ANGPT4 pAb in paraffin-embedded human stomach carcinoma tissue at 1:50,showing secreted staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.