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DEFB4 polyclonal antibody

货号: BS60360

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60360

Product Name :DEFB4 polyclonal antibody

Swiss-Prot :O15263

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :β-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DEFB4 polyclonal antibody detects endogenous levels of DEFB4A/DEFB4B protein.

BiowMW :~ 7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Beta-defensin 4A; Beta-defensin 2; BD-2; hBD-2; Defensin beta 2; Skin-antimicrobial peptide 1; SAP1; DEFB4A; DEFB102, DEFB2, DEFB4; DEFB4B; β-defensin 4A; Defensin-β2; Defensin β2

Immunogen :A synthetic peptide corresponding to residues in Human DEFB4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DEFB4 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate

Aged garlic extract enhances the production of β‑defensin 4 via activation of the Wnt/β‑catenin pathway in mouse gingiva

Journal10.3892/etm.2024.12791

ApplicationWB

IF2.4

SpeciesMouse

PMID39781190