产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

EDN1 polyclonal antibody

货号: BS6036

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6036

Product Name :EDN1 polyclonal antibody

Swiss-Prot :P05305

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :The human endothelins represent a gene family comprised of endothelin-1, endothelin-2, and endothelin-3, also known as ET-1, ET-2, and ET-3. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. The two receptor subtypes responsible for inducing vasoconstriction and vasodilation, ETA and ETB, have different receptor affinities for ET-1, ET-2, and ET-3. Of the three isopeptides, ET-2 has the most potent vasoconstrictor activity (1). Biologically active ETs are proteolytically generated from a larger precursor, the big-endothelin, by action of the endothelin-converting enzyme (ECE) family. ET-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :EDN1 polyclonal antibody detects endogenous levels of EDN1 protein.

BiowMW :~ 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Big endothelin 1; Big endothelin-1; EDN 1; EDN1; EDN1 protein; EDN1; Endothelin1; ET 1; ET-1; ET1; OTTHUMP00000039245; PPET 1; PPET1; Preproendothelin 1; Preproendothelin-1; Preproendothelin1

Immunogen :Synthetic peptide, corresponding to Human EDN1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of EDN1 pAb at 1:500 dilution LaneA:HEK293T whole cell lysate(40ug) LaneB:LOVO whole cell lysate(40ug) LaneC:H1792 whole cell lysate(40ug) LaneD:The Testis tissue lysate of Mouse(40ug)