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Cytokeratin 84 polyclonal antibody

货号: BS60302

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60302

Product Name :Cytokeratin 84 polyclonal antibody

Swiss-Prot :Q9NSB2

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The Keratin multigene family is made of “soft” epithelial cytokeratins and “hard” hair Keratins. While the epithelial cytokeratins are involved in the layering and formation of epithelia, the hair Keratins are responsible for creating nails and hair. There are two types of Keratins: the acidic class I Keratin proteins and the basic/neutral class II Keratin proteins. Keratin 84, also known as KRT84, HB4 or KRTHB4, is a 600 amino acid protein that is expressed in hair follicles. Keratin 84 is a basic/neutral type II Keratin protein which heterodimerizes with type I Keratins to create hair and nails. The gene encoding Keratin 84 maps to human chromosome 12 which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cytokeratin 84 polyclonal antibody detects endogenous levels of Cytokeratin 84 protein.

BiowMW :~ 65 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cytokeratin-84; Keratin, type II cuticular Hb4; Keratin-84; Keratin84; Short name=K84; Type II hair keratin Hb4; Type-II keratin Kb24; KRT84; KRTHB4

Immunogen :A synthetic peptide corresponding to residues in Human Cytokeratin 84.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cytokeratin 84 polyclonal antibody at 1:500 dilution Lane1:THP-1 cell lysate Lane2:Raw264.7 cell lysate Lane3:PC12 cell lysate