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DGAT2 polyclonal antibody

货号: BS60142

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS60142

Product Name :DGAT2 polyclonal antibody

Swiss-Prot :Q96PD7

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DGAT2 polyclonal antibody detects endogenous levels of DGAT2 protein.

BiowMW :~ 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Diacylglycerol O-acyltransferase 2; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; Retinol O-fatty-acyltransferase; Diglyceride acyltransferase 2; DGAT2; HMFN1045; UNQ738/PRO1433

Immunogen :A synthetic peptide corresponding to residues in Human DGAT2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DGAT2 pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:AML-12 whole cell lysate(40ug) Lane3:A375 whole cell lysate(40ug) Lane4:L02 whole cell lysate(40ug) Lane5:HepG2 whole cell lysate(40ug)

Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse

JournalEcotoxicology And Environmental Safety

ApplicationWB

IF6.291

SpeciesMouse

PMID34695613
Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish

JournalCommunications Biology

ApplicationIHC

IF4.165

SpeciesZebrafish

PMID31372513