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AGP-2 polyclonal antibody

货号: BS60097

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS60097

Product Name :AGP-2 polyclonal antibody

Swiss-Prot :P19652

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :AGP (a 1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/ml, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP-1, AGP-2, AGP-3 and AGP-8. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AGP-2 polyclonal antibody detects endogenous levels of AGP-2 protein.

BiowMW :~ 24, 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Alpha-1-acid glycoprotein 2; AGP 2; Orosomucoid-2; Orosomucoid 2; Orosomucoid2; OMD 2; OMD2; ORM2; ORM-2; AGP2

Immunogen :A synthetic peptide corresponding to residues in Human AGP-2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of AGP-2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:H9C2 whole cell lysate

Immunohistochemistry (IHC) analyzes of AGP-2 pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50,showing secreted and membrane staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Immunohistochemistry (IHC) analyzes of AGP-2 pAb in paraffin-embedded human liver carcinoma tissue at 1:50,showing secreted and membrane staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase