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EFTUD2 polyclonal antibody

货号: BS5939

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5939

Product Name :EFTUD2 polyclonal antibody

Swiss-Prot :Q15029

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC ICC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200

Background :Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA. Snrp116, also known as EFTUD2 (elongation factor Tu GTP binding domain containing 2) or Snu114, is a 972 amino acid protein that localizes to the nucleus and belongs to the GTP-binding elongation factor family. Existing as a component of the multi-protein U5 snRNP spliceosome complex, Snrp116 plays an important role in pre-mRNA splicing, as well as in the recycling of spliceosomal snRNPs. The gene encoding Snrp116 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :EFTUD2 polyclonal antibody detects endogenous levels of EFTUD2 protein.

BiowMW :~ 116 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :116 kDa U5 small nuclear ribonucleoprotein component; Elongation factor Tu GTP-binding domain-containing protein 2; SNU114 homolog; Hsnu114; U5 snRNP-specific protein, 116 kDa; U5-116 kDa; KIAA0031; SNRP116

Immunogen :Synthetic peptide, corresponding to amino acids 371-416 of Human EFTUD2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of EFTUD2 polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate