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GLUL polyclonal antibody

货号: BS5734

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS5734

Product Name :GLUL polyclonal antibody

Swiss-Prot :P15104

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Glutamine synthetase (GI Syn) forms a homooctamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GLUL polyclonal antibody detects endogenous levels of GLUL protein.

BiowMW :~ 49 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Glutamine Metabolism,

Alternative Name :Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase; GLNS; Gl Syn

Immunogen :Synthetic peptide, corresponding to amino acids 328-373 of Human GLUL.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of GLUL polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Mouse kidney tissue lysate Lane3:H9C2 cell lysate