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ADH7 polyclonal antibody

货号: BS5600

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS5600

Product Name :ADH7 polyclonal antibody

Swiss-Prot :P40394

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :ADH7 (alcohol dehydrogenase 7 (class IV), µ or σ polypeptide), is a 386 amino acid protein belonging to the zinc-containing alcohol dehydrogenase family and the class-IV subfamily. Seven different human ADH isozymes exist: three belong to class-I: α, β and γ; one to class-II: π; one to class-III: χ; one to class-IV: ADH7; and one to class-V: ADH6. Encoded by a gene that maps to human chromosome 4q23, ADH7 localizes to the cytoplasm and is preferentially expressed in stomach, but, unlike other family members, is absent from liver. ADH7 is a homodimer that binds two zinc ions per subunit and contains nine exons. ADH7 participates in the synthesis of retinoic acid, a hormone important for cellular differentiation. Variations in ADH7 may be associated with alcohol dependence. ADH7 may also play a role in protection against aerodigestive tract cancer.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ADH7 polyclonal antibody detects endogenous levels of ADH7 protein.

BiowMW :~ 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Alcohol dehydrogenase class 4 mu/sigma chain; Alcohol dehydrogenase class IV mu/sigma chain; Gastric alcohol dehydrogenase; Retinol dehydrogenase; ADH7

Immunogen :A synthetic peptide corresponding to residues in Human ADH7.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ADH7 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:PC12 cell lysate