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Epac1 Recombinant Rabbit mAb (KU)

货号: BS49612

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS49612

Product Name :Epac1 Recombinant Rabbit mAb (KU)

Swiss-Prot :O95398

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB: 1:1000-1:5000<br />IHC: 1:100

Background :Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :104 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EPAC; EPAC1; bcm910; HSU79275; CAMP-GEFI

Immunogen :A synthetic peptide of human Epac1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Epac1 in 3T3 cell lysates using Epac1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）