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Notch1 Recombinant Rabbit mAb (KU)

货号: BS49560

价格：￥ 700

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS49560

Product Name :Notch1 Recombinant Rabbit mAb (KU)

Swiss-Prot :P46531

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC,ICC/IF,FC

Application_all :WB: 1:1000<br />IHC: 1:100-1:200<br />ICC/IF: 1:100-1:200<br />FC: 1:100-1:200

Background :This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :hN1; AOS5; TAN1; AOVD1

Immunogen :A synthetic peptide of human Notch1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Notch1 in C6,Hela cell lysates using Notch1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）