Product Name :Acetyl Coenzyme A carboxylase alpha Recombinant Rabbit mAb (KU)
Swiss-Prot :O00763, Q5SWU9, P11497
Reactivity :Human,Mouse,Rat
Applications :WB, IHC, ICC/IF, FC, IP
Application_all :WB: 1:1000-1:2000<br />IHC: 1:200-1:500<br />ICC/IF: 1:50<br />FC: 1:200-1:500<br />IP: 1:20
Background :Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ACC; ACAC; ACC1; ACCA; ACACAD
Immunogen :Recombinant protein of human Acetyl Coenzyme A carboxylase alpha
Modification :Unmodification
