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IDE Recombinant Rabbit mAb (KU)

货号: BS49521

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS49521

Product Name :IDE Recombinant Rabbit mAb (KU)

Swiss-Prot :P14735

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,FC

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100

Background :This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009]

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 45 kDa; Observed MW: 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PGKA; MIG10; HEL-S-68p

Immunogen :A synthesized peptide derived from human PGK1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PGK1 in HepG2 lysates; mouse kidney lysates using PGK1 antibody.

Western blot analysis of PGK1 in SKOV-3, Jurkat, U251, PC-3 and Hela lysates using PGK1 antibody.