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DCAMKL1 Recombinant Rabbit mAb (KU)

货号: BS49504

价格：￥ 700

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS49504

Product Name :DCAMKL1 Recombinant Rabbit mAb (KU)

Swiss-Prot :O15075

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:50<br />ICC/IF: 1:50

Background :This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :82 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CL1; DCLK; CLICK1; DCDC3A; DCAMKL1

Immunogen :A synthetic peptide of human DCAMKL1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of DCAMKL1 in Rat Brain lysates using DCAMKL1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）