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Caspase-8 Recombinant Rabbit mAb (KU)

货号: BS49389
价格 700
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS49389
Product Name :Caspase-8 Recombinant Rabbit mAb (KU)
Swiss-Prot :Q14790
Host :Rabbit
Reactivity :Human, Mouse, Rat
Applications :WB,IHC
Application_all :WB: 1:1000<br />IHC: 1:200-1:500
Background :This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq, Jul 2008]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :IgG
BiowMW :55 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
Immunogen :A synthetic peptide of human Caspase-8
Conjugate :Unconjugated
Modification :Unmodification

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com