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hnRNP K (phospho-S284) polyclonal antibody（KU）

货号: BS4805

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS4805

Product Name :hnRNP K (phospho-S284) polyclonal antibody（KU）

Swiss-Prot :P61978

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K, a 65 kDa protein, recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-hnRNP K (S284) pAb detects endogenous levels of hnRNP K protein only when phosphorylated at Ser284.

BiowMW :~ 58 to 62 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP; HNRNPK; HNRPK

Immunogen :Synthetic phosphopeptide derived from human hnRNP K around the phosphorylation site of Serine 284

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-hnRNP K (S284) pAb at 1:500 dilution Lane1:Hela whole cell lysate(40µg) Lane2:HEPG2 whole cell lysate(40µg) Lane3:CT-26 whole cell lysate(40µg) Lane4:C6 whole cell lysate(40µg)