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FKHR/FoxO1 (phospho-S256) polyclonal antibody

货号: BS4711
价格 1350
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS4711
Product Name :FKHR/FoxO1 (phospho-S256) polyclonal antibody
Swiss-Prot :Q12778
Host :Rabbit
Reactivity :Human,Mouse
Applications :WB IHC IF
Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Background :FOXO1A (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Chromosomal aberrations involving FOXO1A are a cause of rhabdomyosarcoma 2 (RMS2); also known as alveolar rhabdomyosarcoma.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :p-FoxO1 (S256) polyclonal antibody detects endogenous levels of FoxO1 protein only when phosphorylated at Ser256.
BiowMW :~ 70 to 82 kDa
Note :For research use only, not for use in diagnostic procedure.
Pathway :Insulin &Glucose Signaling,Cell Cycle Control G1 S Checkpoint,
Alternative Name :Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma; FOXO1; FKHR; FOXO1A
Immunogen :Synthetic phosphopeptide derived from human FKHR around the phosphorylation site of Serine 256.
Conjugate :Unconjugated
Modification :Phosphorylation
  • Effects of neonatal dexamethasone administration on cardiac recovery ability under ischemia-reperfusion in 24-wk-old rats
    JournalPediatric Research
    ApplicationWB
    IF2.88
    SpeciesRat

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com