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FoxO4 (phospho-T451) polyclonal antibody

货号: BS4687

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS4687

Product Name :FoxO4 (phospho-T451) polyclonal antibody

Swiss-Prot :P98177

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-FoxO4 (T451) polyclonal antibody detects endogenous levels of FoxO4 protein only when phosphorylated at Thr198.

BiowMW :~ 70 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Forkhead box protein O4; Fork head domain transcription factor AFX1; AFX; AFX1; MLLT7; FOXO4

Immunogen :Synthetic phosphopeptide derived from human FoxO4 around the phosphorylation site of Threonine 451.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-FoxO4 (T451) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:HepG2 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:H9C2 whole cell lysate(40ug) Lane5:AML-12 whole cell lysate(40ug)