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Cytokeratin 18 (phospho-S52) polyclonal antibody（KU）

货号: BS4588

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS4588

Product Name :Cytokeratin 18 (phospho-S52) polyclonal antibody（KU）

Swiss-Prot :P05783

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin isoforms demonstrate tissue and differentiation-specific profiles that make them useful as research biomarkers. Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-Cytokeratin 18 (S52) polyclonal antibody detects endogenous levels of Cytokeratin 18 protein only when phosphorylated at Ser52.

BiowMW :~ 46 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of Soluble Factors to EMT,

Alternative Name :Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18; KRT18; CYK18; PIG46

Immunogen :Synthetic phosphopeptide derived from human Cytokeratin 18 around the phosphorylation site of Serine 52

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of p-Cytokeratin 18 (S52) polyclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate(40µg) Lane2:L02 whole cell lysate(40µg) Lane3:A549 whole cell lysate(40µg)

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