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Cytokeratin 8 (phospho-S432) polyclonal antibody （KU）

货号: BS4323

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS4323

Product Name :Cytokeratin 8 (phospho-S432) polyclonal antibody （KU）

Swiss-Prot :P05787

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin isoforms demonstrate tissue and differentiation-specific profiles that make them useful as research biomarkers. Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cytokeratin 8 (phospho-S432) polyclonal antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at Ser432.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of Soluble Factors to EMT,

Alternative Name :Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a; CSNK2B; CK2N, G5A

Immunogen :Synthetic phosphopeptide derived from human Casein Kinase IIβ around the phosphorylation site of Serine 209

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot (WB) analysis of Cytokeratin 8 (phospho-S432) polyclonal antibody at 1:500 dilution Lane1:PC3 whole cell lysate(20µg) Lane2:MCF-7 whole cell lysate(20µg) Lane3:Hela whole cell lysate(20µg) Lane4:A549 whole cell lysate(20µg) Lane5:The Lung tissue lysate of Mouse(20µg)