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G3BP-1 (phospho-S232) polyclonal antibody

货号: BS4077

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS4077

Product Name :G3BP-1 (phospho-S232) polyclonal antibody

Swiss-Prot :Q13283

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p-G3BP-1 (S232) polyclonal antibody detects endogenous levels of G3BP-1 protein only when phosphorylated at Ser232.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :G3BP1; G3BP; hDH VIII; G3BP-1; Ras GTPase-activating protein-binding protein 1; GAP SH3 domain-binding protein 1

Immunogen :Synthetic phosphopeptide derived from human G3BP-1 around the phosphorylation site of Serine 232.

Conjugate :Unconjugated

Modification :Phosphorylation

Immunohistochemistry (IHC) analyzes of p-G3BP-1 (S232) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）