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DHS (L87) polyclonal antibody（KU）

货号: BS3847

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3847

Product Name :DHS (L87) polyclonal antibody（KU）

Swiss-Prot :P49366

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Deoxyhypusine synthase (DHS) is crucial for the posttranslational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A). Hypusine is formed by posttranslational modifications involving two enzymatic steps catalyzed by DHS and deoxyhypusine hydroxylase (DOHH). eIF-5A is essential for eukaryotic cell proliferation. DHS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. It acts as a catalyst for the NAD-dependent oxidative cleavage of spermidine and the ensuing transfer of the butylamine moiety of spermidine to the eIF-5A protein, to create the intermediate deoxyhypusine residue.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DHS (L87) polyclonal antibody detects endogenous levels of DHS protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Deoxyhypusine synthase; DHPS; DS

Immunogen :Synthetic peptide, corresponding to amino acids 50-100 of Human DHS.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of DHS (L87) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:PC3 whole cell lysate(40ug) Lane5:MCF-7 whole cell lysate(40ug)