Product Name :EphB1/2/3/4 (Y594) polyclonal antibody
Swiss-Prot :P54762/P29323/P54753/P54760
Application_all :IHC: 1:50~1:200
Background :Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :EphB1/2/3/4 (Y594) polyclonal antibody detects endogenous levels of EphB1/2/3/4 protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Tumor Angiogenesis,Tumor Angiogenesis,
Alternative Name :EphB1; EphB2; EphB3; EphB4;
Immunogen :Synthetic peptide, corresponding to amino acids 560-610 of Human EphB1.
Modification :Unmodification
