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ACTR-IIA (H59) polyclonal antibody（KU）

货号: BS3669

价格：￥ 660

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3669

Product Name :ACTR-IIA (H59) polyclonal antibody（KU）

Swiss-Prot :P27037

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (ACVR2A) or ACTR-IIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ACTR-IIA (H59) polyclonal antibody detects endogenous levels of ACTR-IIA protein.

BiowMW :~ 58 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Activin receptor type-2A; EC=2.7.11.30; Activin receptor type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2

Immunogen :Synthetic peptide, corresponding to amino acids 30-80 of Human ACTR-IIA.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of ACTR-IIA (H59) pAb at 1:500 dilution Lane1:AML-12 whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug)