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Annexin 2 (N137) polyclonal antibody（KU）

货号: BS3553

价格：￥ 660

货期：现货（1-2个工作日）

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No. :BS3553

Product Name :Annexin 2 (N137) polyclonal antibody（KU）

Swiss-Prot :P07355

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Annexin 2 (N137) polyclonal antibody detects endogenous levels of Annexin 2 protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36; ANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin2;

Immunogen :Synthetic peptide, corresponding to amino acids 111-160 of Human Annexin 2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Annexin 2 (N137) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:MCF-7 cell lysate Lane3:Raw264.7 cell lysate Lane4:H9C2 cell lysate

Immunohistochemistry (IHC) analyzes of Annexin 2 (N137) pAb in paraffin-embedded human breast carcinoma tissue at 1:50,showing membrane and cytoplasmic staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in Tumorigenesis and Metastasis

JournalBMC Medical Genomics

ApplicationWB

IF3.063

SpeciesHuman

PMID