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Defensin α4 (D27) polyclonal antibody

货号: BS3497

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3497

Product Name :Defensin α4 (D27) polyclonal antibody

Swiss-Prot :P12838

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC:1:50~1:200

Background :Human neutrophil alpha-defensins (also designated HNPs) are small, cationic,cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice.The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Defensin α4 (D27) polyclonal antibody detects endogenous levels of Defensin α4 protein.

BiowMW :~ 11 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Neutrophil defensin 4; Defensin; alpha 4; HNP-4; HP-4; DEFA4; DEF4; α-defensin 4

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human Defensin α4.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of Defensin α4 (D27) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）