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IL-8 (V68) polyclonal antibody

货号: BS3479

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3479

Product Name :IL-8 (V68) polyclonal antibody

Swiss-Prot :P10145

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :IL-8 has been shown to function as a potent neutrophil chemostatic and activating peptide and is an important mediator of inflammatory diseases. Two distinct human IL-8 receptors, designated IL-8RA and IL-8RB, have been characterized. Both are expressed at a high level on neutrophils, and to a lesser extent on monocytes and myeloid cell lines. In addition, the IL-8RA subunit is expressed in T cells such as the Jurkat cell line. Both IL-8Rs are members of the seven-transmembrane domain rhodopsin superfamily of receptors and as such, couple G proteins for signal transduction. The two receptors share 77% amino acid identity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-8 (V68) polyclonal antibody detects endogenous levels of IL-8 protein.

BiowMW :~ 11 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1 Protein 3-10C; T-cell chemotactic factor; CXCL8; IL8

Immunogen :A synthetic peptide corresponding to residues in Human IL-8.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of IL-8 pAb at 1:500 dilution Lane1:THP-1 treated with LPS(100 ng/ml) for 6h and treated with BFA(300 ng/ml) for 3h whole cell lysate(30ug) Lane2:THP-1 whole cell lysate(30ug)

Immunohistochemistry (IHC) analyzes of IL-8 (V68) pAb in paraffin-embedded human lung carcinoma tissue at 1:100.

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