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AQP5 (Y243) polyclonal antibody

货号: BS3477

价格：￥ 660

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3477

Product Name :AQP5 (Y243) polyclonal antibody

Swiss-Prot :P55064

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AQP5 (Y243) polyclonal antibody detects endogenous levels of AQP5 protein.

BiowMW :~ 36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Aquaporin-5; AQP-5; Aquaporin5; AQP5; Aquaporin 5; AQP 5;

Immunogen :Synthetic peptide, corresponding to amino acids 220-270 of Human AQP5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of AQP5 (Y243) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(20ug) Lane3:PC12 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of AQP5 (Y243) pAb in paraffin-embedded human lung carcinoma tissue at 1:100.

A decrease in the tear secretion volume in a mouse model with ulcerative colitis

JournalCutaneous And Ocular Toxicology

ApplicationWB

IF1.82

SpeciesMouse

PMID32942916
Improvement effect of gemigliptin on salivary gland dysfunction in exogenous methylglyoxal-injected rats

JournalHeliyon

ApplicationWB,IHC

IF4

SpeciesRat

PMID38628768