Product Name :BMP-6 (A152) polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
Background :In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFβ receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :BMP-6 (A152) polyclonal antibody detects endogenous levels of BMP-6 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Bone morphogenetic protein 6; BMP-6; VG-1-related protein (VG-1-R; VGR-1); BMP6; VGR
Immunogen :A synthetic peptide of human BMP-6.
