Product Name :FucT-IV (E71) polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :IHC: 1:50~1:200
Background :FucT-IV (α 1,3-fucosyltransferase IV), also known as FUT4, FCT3A or ELFT, is a 405 amino acid single-pass type II membrane protein that localizes to Golgi stacks. During embryogenesis, FucT-IV is highly expressed in skin, liver, kidney, muscle and small intestine where it functions to catalyze the glycosidic attachment of α-fucose to various molecules, such as N-acetyllactosamines. Via its catalytic activity, FucT-IV participates in the synthesis of carbohydrate molecules like the cell-adhesion antigen CD15 (also known as Lewis X), thereby playing a roll in cell cycle events such as apoptosis and cellcell binding. Overexpression of FucT-IV is implicated in epithelial cancers, suggesting a possible role for FucT-IV in carcinogenesis.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :FucT-IV (E71) polyclonal antibody detects endogenous levels of FucT-IV protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Tumor-Infiltrating Immune Cell Marker Guide,ESC Pluripotency and Differentiation Signaling Pathway,
Alternative Name :Alpha-(1,3)-fucosyltransferase 4; ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV; Fuc-TIV; FucT-IV; Galactoside 3-L-fucosyltransferase; FUT4; ELFT; FCT3A
Immunogen :Synthetic peptide, corresponding to amino acids 45-90 of Human FucT-IV.
Modification :Unmodification
