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AQP4 (P253) polyclonal antibody（KU）

货号: BS3436

价格：￥ 660

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3436

Product Name :AQP4 (P253) polyclonal antibody（KU）

Swiss-Prot :P55087

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AQP4 (P253) polyclonal antibody detects endogenous levels of AQP4 protein.

BiowMW :~ 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Aquaporin 4; Aquaporin4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4; AQP4

Immunogen :Synthetic peptide, corresponding to amino acids 220-270 of Human AQP4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of AQP4 (P253) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Jurkat cell lysate Lane3:PC12 cell lysate Lane4:sp2/0 cell lysate

Immunohistochemistry (IHC) analyzes of AQP4 (P253) pAb in paraffin-embedded human lung carcinoma tissue.

miRNA-320a inhibits glioma cell invasion and migration by directly targeting aquaporin 4

JournalOncology Reports

ApplicationWB,IHC

IF3.417

SpeciesHuman

PMID29484417